No idea if this has been hyped all to hell or not, but being a 2 part 48 page comic is great for people like me, who have stopped collecting single books (Honestly, it comes down to weight. I decided I wasn't going to move more than one box the last time we moved, and sold/gave most of my collection away to a friend.) One of the few comics I did keep is the last time Gaiman wrote Batman (With a really cute cameo by John Constantine) so, I will likely ask my brother to go pick this up for me. Not sure if this plays off of the Morrison stuff or not, but it looks fun.
My bet: Lady Master Chief is Lana, who has superpowers and emits Kryptonite but went to space to try to figure out how to get un-Kryptonited. Hence, the suit, so she can be around Clark and not kill him by heebie jeebies.