I also believe that the situation was avoidable. When Shane and Otis both went into the medical trailer, I immediately knew that it was going to be a mistake because there was no one outside to arrange the escape. That's one of the things that I think makes Shane more of a "villain," it's not just that he'll do whatever he thinks he needs to do to survive or help Carl and Lorie, it's that he's reckless. Instead of making a plan ahead of time, Shane just charged in, and when push came to shove, of course he fed Otis to the zombies.
I wasn't able to catch the episode in its entirety, but I'm very glad I saw the embedded interview. Russell Brand had me rolling! "I feel bad promoting my own productions all the time, so... Hats! Perhaps you'd like a hat. You should get one.