I'm surprised I haven't seen more talk about San Andreas on here lately. About two weeks ago, GameSpot and IGN released features on the game. It appears they got the info for their features from the same meeting with game execs. I also stumbled across this site, which (if believable) has a lot of cool info about the game. Grr, 10/26 will never get here.
Go ahead and pick it up. I did, and I haven't looked back yet. The improved submission gameplay alone makes it worth the money. Now instead of just laying on a beatdown, I have the option to put on an actual catch-style matchup.