I was wondering if any of you fine people have been on this medication. My doctor started me on it this week (for depression and anxiety)and it is a bit odd. I am tired all the time, no matter how much sleep I get. When I close my eyes, it's like a Pink Floyd Laser show going on. Tons of swirling green, red, and purple lights. Swirling until I go to sleep.
Overall my mood is better, but I just don't 'feel' right.
"Put on your helmets, we'll be reaching speeds of 3!" "It was nice of you to give that dead woman another chance." "All right, look alive everybody...oh sorry Susan."- MST3K: Space Mutiny Click Here (myspace.com)
Good god, man...with side effects like that, I gotta wonder if the treatment is worse than the symptoms.
Originally posted by above linkCommon side effects of mirtazapine may include dizziness, blurred vision, sedation, drowsiness or somnolence, malaise or lassitude, increased appetite or hyperphagia and subsequent weight gain, agitation or restlessness, irritability or aggression, apathy or anhedonia or emotional blunting, excessive mellowness or calmness, dry mouth or xerostomia, difficulty swallowing or dysphagia, shallow breathing or hypoventilation or respiratory depression, constipation, decreased body temperature or hypothermia, pupil constriction or miosis, enhanced libido and sexual function or aphrodisia, wet dreams or nocturnal emission, spontaneous orgasm, loss of balance, vertigo, and restless legs syndrome (RLS) Mirtazapine has also occasionally been reported to cause mild psychedelic effects in some patients, including mental imagery, auditory and visual hallucinations, and particularly, vivid, bizarre, and even lucid dreams or nightmares. Most of these side effects are generally mild and become less prominent with chronic dosing over time.
Rare and potentially serious adverse reactions may include allergic reaction, abnormal fluid accumulation or edema, fainting or syncope, seizures or convulsions, bone marrow suppression or myelotoxicity, ineffective myeloid blood cell production or myelodysplasia, and white blood cell reduction or agranulocytosis (occurs in 1/1,000 patients).
Mirtazapine may not cause most of the side effects encountered with related antidepressants such as decreased appetite or anorexia, insomnia, nausea and vomiting or emesis, diarrhea, urinary retention or ischuria, increased body temperature or hyperthermia, increased perspiration or sweating, pupil dilation or mydriasis, or sexual dysfunction (consisting of loss of libido and anorgasmia), can have the capacity to exacerbate a patient's depression or anxiety or cause suicidal ideation, although this is rare but the patient should be aware of these risks which are also possible any point, if discontinuation and withdrawal occour abruptly.
I mean, I'm all for curing and treating personal and psychological issues, and to help the body run as the perfectly oiled machine God (or Allah/Xenu/whomever) created, but when I see ads on American TV stations for the Latest And Greatest Medication Available (insert exclamation marks here) which have a laundry list of side effects that can range from minor (dry throat) to major (heart failure), I gotta wonder whether things are being taken a bit too far.
(edited by Oliver on 18.8.09 0916)
(edited by Oliver on 18.8.09 0919) "I have a feeling that waiting isn't as pointless as it seems. If someone is waiting, that place becomes a place to return to."
Yeah, definitely talk to your doctor, and be very clear how much (or how little) you think the medication is actually helping you. There are all kinds of meds for psychiatric issues, and having known a couple people who suffered from depression I know that finding the correct meds can be a more involved process than you might think. Don't be afraid to ask your doctor to try something else if you're unhappy with the results Remeron is giving you.
Preamble Everybody's depression is different Everybody reacts to medication differently When in doubt, speak to your doctor Also, speak to your pharmacist. They often know more about drugs than your doctor. Don't be afraid to get a second opinion if you are able and what the first doc says doesn't feel right. I am not a doctor, or a lawyer or plumber for that matter either. I can probably talk authoritatively about C#.
Body I've not taken the Remeron brand, but I did take Mirtzapine for about 2.5 years (30mG per day) This is how I was affected - it may not relate to you at all, please don't take is as gospel, see you doctor, etc. Also, I was on other drugs at the same time - mood stabilizers, and even more drugs to mitigate the side effects caused by the first two, so my attribution of symptoms may be incorrect.
I found it took about two weeks for them to settle down. I didn't have swirling colours, etc (or no more than previously). Tiredness - Yep, and this was constant for the entire time I was on the drug. It was a crazy type of tired too. You just didn't wake up. I found that if I was to be any chance of getting up in time for work in the morning I had to take the pill no later than 9pm, which meant I was asleep in the armchair by 10pm - and I'd never done that before. Apathy- this was probably caused by both drugs. While is was certainly a better person medicated. I stopped flying off the handle and a bonus side effect was an ability to tolerate fools. The bottom line was Not much made me give a fuck. The problem was, I also stopped giving a fuck about things that I should have been giving a fuck about. This attitude almost cost me my job, and was the last straw in my marriage. Loss of Libido - wasn't interested at all. everything still worked, just no drive. Weight Gain - This was supposed to be mainly the other drug where weight gain is the norm, but I include it for completeness. I stacked on about 30kgs in about a month and a half. Stupidness - not a listed side effect, and probably the manifestation of a number of side effects, but I find it describes the symptoms well. I am an IT professional (software), and I was employed at a fairly senior level. I found that I was not able to perform at the level expected of me in this role, or at the level that led me to get that role in the first place. I really struggled to sit down and design a software system that would solve a given problem - something I could previously (and subsequently) do in my sleep. Also there was the facet of emotional range. I couldn't process complex emotions and emit appropriate responses. To give an example, if I was at a funeral, I could process that this was sad, but dealing with sad took all my attention. I couldn't handle the thought process that would make me think, hey if I'm sad, then my wife is probably sad too. I should give her a hug. It just never occurred to me. To me this was more horrible than how I behaved before I got on the drugs.
Now these side effects were annoying on their own, but you got a stacking effect as well, eg Weight Gain / Apathy- but I didn't have the drive to seriously get it under control. Stupidness / Apathy - couldn't do my job properly, but that didn't really worry me. Libido / Stupidness / Apathy - no interest, not smart enough to figure out the effect this was having on my marriage, didn't have the drive to do anything about it. Tired / Apathy - didn't have the drive to get out of bed and fight through the drug induced drowsiness hangover.
As I'm sure you're aware, there are other non-drug ways of combating depression. I didn't have the drive to employ these techniques.
The main problem with me was that I knew I had given my wife hell previously, and I desperately wanted this to work so much so that I was afraid to change the drugs in case I reverted. In the end I reduced the levels mainly to address the tiredness, stupidity and libido side effects. Once I had stabilized, I came to the realization that I was never going to get my life in order while I was on that particular cocktail. As mentioned above the cure was worse than the cause. I had changed to an easier, lower pressure job and I was living by myself as my marriage was over by this point. I was chronically obese and heart disease or diabetes was certainly on the horizon. So, with the help of my doctor, I spent the next 4 months weaning my self off everything, gradually with stabilization points, kinda like decompression stops when scuba diving. This process has taught me a lot about how my body and mind (my mind, not minds in general) work, warning signs, etc. so I feel better armed about combating this. Some days are a struggle, some days I'm a prick - but now I can often see it coming and take containing action. I'm still fat, but it's improving.
Originally posted by Tenken347 Don't be afraid to ask your doctor to try something else if you're unhappy with the results Remeron is giving you.
This is probably the best thing written here. It's your health, so you need to be happy with the results. Sure you need to let yourself stabilize like your doc says for 2-4 weeks, but Please don't do what I did and just ride it out because you're too scared to make adjustments. Talk to you family about how you're feeling (Tuff at the best of times for us blokes) They will probably see things you or your doc can't - especially if you're suffering from the dumbening. Take your wife to the doc with you too.
Depression is a fucker and I really feel for you. Feel free to shoot me a message if you ever need a chat.
Final tip This is one I've found most medics miss. The drug you are on has a withdrawal effect, as you know. What you need to watch is if you get a gastro bug and are not keeping stuff in, you will not absorb your meds properly, withdrawer, and become a prick. So be careful and take the appropriate action quickly.
The advice regarding withdrawal is important. Our daughter was diagnosed with OCD (not much fun for her) and depression. They slowly ramped her meds up and then eased them back down. Her depression med (can't remember which one) affected her in a manner similar too you and she adjusted after a couple weeks. When she went off, it took a month to wean her. They did the same for the OCD med but after it was out of her system, it was quickly apparent she needed it and they put her back on it. And those saying talk to your pharmacist are right as they know the drugs better than the docs.
I say just do it and go home. Only the select 1% of the population (maybe less) get to do something for a living that they already enjoy anyway, and the rest of us just end up doing something we happen to know how to do.