Among her most famous works, she wrote When Harry Met Sally (including one of the most famous movie lines of all time: "I'll have what she's having."), and directed Sleepless in Seattle, You've Got Mail, and Julie and Julia.
“@ZackRyder: @CMPunk She played me bro” I got your back.
Bad day for nerds. First Dwayne McDuffie, then the Brig from Doctor Who. Age 81. http://www.bbc.co.uk/news/entertainment-arts-12549622 tom baker's appreciation: http://www.tom-baker.co.uk/pages/content/index.asp?PageID=159