AVENGERS/INVADERS #3: It's Namor (circa now) vs. Namor (circa WWII). Fans of the Sub-Mariner shouldn't miss this.
HULK #5: Those disappointed by the startling omission of a certain dream match during World War Hulk can rest easy. It's Red Hulk vs. Thor! Yes!
NOVA #15: This month seems to feature a whole bunch of awesome one-on-one fights. This time, it's Nova vs. Galactus! Score!
AVENGERS: THE INITIATIVE #15: The tease hints that this will mark the return of the Skrull Kill Krew!
BLACK PANTHER #39: Reginald Hudlin don't live here no more. Jason Aaron takes a title left in shambles and attempts to resurrect it by tying it to "Secret Invasion". He's already worked magic on "Wolverine". Let's see if he can do the same with T'Challa.
THUNDERBOLTS #122: Ellis-haters can rest easy, as Christos Gage takes over for this arc. Captain Marvel has attacked Thunderbolts Mountain (as seen in "Secret Invasion #1"). The T-bolts will try and take him out, but likely take each other out along the way.
ASTONISHING X-MEN #25: Ellis-haters can groan audibly. The Warren Ellis era of AXM officially begins.
UNCANNY X-MEN #500: The mutant title reaches its milestone 500th issue. A new era begins (again) with Ed Brubaker and Matt Fraction taking over.
Feels like more to get excited about on Marvel's end, even when you completely discount the "Secret Invasion" stuff.
I didn't hate the Ellis run on Thunderbolts, but I'm glad to see him off the book. I know I'm not the first to say this, but Ellis' book was too much Suicide Squad, and not the Thunderbolts book I followed for 118 issues. I think Gage is a good fit for the book, his one-shots have been getting better as he goes along, and he seems to have a good grasp of what the book was before Ellis.
One of the weird things, on paper so far, is the "silver age" X-Men coming to the present and having culture shock. IF you use Marvel's "ten year sliding scale" for their continuity, the original X-Men were likely formed in 2002.