A song that always picks me up and I always end up singing along with is "No Rain" by Blind Melon. Another song that always has an affect on me is "November Rain" by Guns N Roses. Ah, to be a young, depressed college student again.
Pearls before Swine - now available as Vol.2 Graphic Novel with writer's commentary. Dilbert and Ziggy are classics. And all the Far-Side knockoffs can be hit or miss: Close to Home, Pardon our Planet, Rhymes with Orange, Loose Parts,etc.