SECRET SIX #1: Gail Simone's cult hit becomes an ongoing series! And it's about damn time!
JOKER (HARDCOVER): The creative team behind the awesome "Lex Luthor: Man of Steel" take a stab at the Clown Prince of Crime. It promises to be the best Joker story since "The Killing Joke", but we shall see.
GREEN LANTERN #35: The conclusion to "Secret Origin" and the lead-in to October's "Rage of the Red Lanterns".
Other than that, I don't see too much to get excited about, aside from the Final Crisis awesomeness.
I think the Daily Bugle building has been destroyed at least a few times in the past. Graviton ripped the building up into the air twice, and I have a vague collection of a Scorpion-Spidey battle all but trashing the place.