I just watched my first episode of Monk the other night (I believe it was the season premiere) on the recommendation of a friend. I really enjoyed it! Very funny stuff, and Tony Shaloub is great in it.
My favorite comedy, though, other than anything on Adult Swim, is Arrested Development. I don't laugh at anything as hard as I do that show. I'm also really excited about the new episodes of Chappelle's Show coming up.
As for drama right now, it's all about 24 and reruns of The Shield (gearing up for Season 3). I used to watch Law & Order, from almost the first season, but it's just gotten so bad now. In fact, I was going to start watching Karen Sisco instead, but the very week I made that decision, ABC yanked it off their schedule. D'oh!