I know that last year Joe Gibbs threw out a challenge flag when the opposing team had twelve men on the field and the other team was penalized. So, penalties can be reviewed. I don't know if delay of game (or lack of) calls can be reviewed, though.
Well the Louisville win is probably good for Big East fans (unless you're a WVU fan of course). Even though Louisville was lower in the polls and BCS they are actually ranked higher by the computer rankings.